You should have cramping and bleeding after taking the second medication, misoprostol, usually as heavy or heavier than your period. This may include clots or tissue. 

Your pregnancy symptoms such as nausea and breast soreness should start to decrease 24 hours after you have completed treatment, and resolve completely in the weeks after. A urine pregnancy test can stay positive for about 4 weeks after a successful medication abortion due to residual hCG levels, according to ACOG. This is normal, so it’s important not to take a test sooner.